Researchers of the University of Heidelberg, Germany, found that patients with acute inflammation of the pancreas (pancreatitis) showed elevated levels of cannabinoid receptors and endocannabinoids in the pancreas. In studies with mice with pancreatitis a cannabinoid that as THC binds to CB1 and CB2 receptors reduced pain and inflammation of the disease. (Source: Michalski CW, et al. Gastroenterology 2007;132(5):1968-78.)